The Ultimate Key West Visitor Essentials Business Directory
Helpful Local Businesses You’ll Be Glad to Know During Your Stay
Hello and welcome to Key West! This comprehensive Visitor Essentials Business Directory is designed to be copied, saved, bookmarked, or printed for easy reference during your stay. Key West is famously carefree, walkable, and full of character—but once you arrive, practical needs still arise.
Visitors routinely search for grocery stores, pharmacies, clothing, shoes, banking services, gifts, hardware supplies, transportation rentals, medical care, and everyday essentials. This directory exists to solve those moments quickly and clearly.
This guide is intentionally focused on non-restaurant, non-bar, non-hotel businesses that visitors rely on while staying in Key West. Every listing includes exact street addresses and clearly notes whether it is best accessed from Old Town or New Town, helping you save time and stay oriented.
Bookmark this page. It’s one of the most useful resources you’ll have during your visit.
Art Galleries, Framing & Art Supplies (Old Town)
Wyland Galleries Key West
800 Duval St, Key West, FL 33040
Old Town – Duval Street
World-renowned marine-life artwork located directly in the heart of Duval Street.
Cocco & Salem / Imagine Art
1028 Duval St, Key West, FL 33040
Old Town
Contemporary fine art with strong Florida Keys influence.
Gallery on Greene
606 Greene St, Key West, FL 33040
Old Town – Just off Duval
Fine art gallery on a quieter, walkable side street.
Keys Framing & Art Supplies
804 White St, Key West, FL 33040
Old Town – Upper White Street
Custom framing and professional art supplies.
Art On Duval Key West – A Procaccini Gallery
601 Duval St, Key West, FL 33040
Old Town – Lower Duval
Local and international artists with original works and limited-edition prints.
Key West Gallery
601 Duval St, Key West, FL 33040
Old Town – Duval Street
Fine art gallery featuring Florida Keys artists and photography.
Effusion Gallery
701 Duval St, Key West, FL 33040
Old Town – Mid Duval
Contemporary gallery with extended evening hours.
Harrison Gallery
825 Duval St, Key West, FL 33040
Old Town – Upper Duval
Long-established gallery showcasing local and regional artists.
Banks & Financial Services
First State Bank of the Florida Keys (KeysBank)
1201 Whitehead St, Key West, FL 33040
Old Town
Locally owned Keys bank with full-service access downtown.
Gulf Atlantic Bank
333 Fleming St, Key West, FL 33040
Old Town
Community-focused banking near government offices.
Bank of America
3900 N Roosevelt Blvd, Key West, FL 33040
New Town
Convenient for visitors staying near shopping centers.
Truist Bank
1010 Kennedy Dr, Key West, FL 33040
New Town – Key Plaza
Full-service bank with drive-thru and ATM.
First Horizon Bank
2700 N Roosevelt Blvd, Key West, FL 33040
New Town
Regional bank near major retail centers.
Centennial Bank
1400 Kennedy Dr, Key West, FL 33040
New Town
Community bank offering personal and business services.
Desserts & Edible Delights (Retail Treats)
Kermit’s Key Lime Shop
200 Elizabeth St, Key West, FL 33040
Old Town – Harbor Walk
Packaged key lime treats, candies, and gifts.
Key West Sweets
282 Duval St, Key West, FL 33040
Old Town
Candy and chocolate shop ideal for souvenirs.
Key West Key Lime Pie Co.
511 Greene St, Key West, FL 33040
Old Town – Historic Seaport
Retail pies and packaged key lime products.
Peppers of Key West
602 Greene St, Key West, FL 33040
Old Town – Historic Seaport
Specialty hot sauces, spices, and gourmet foods.
Robert Is Here Fruit Stand & Gift Shop
3200 N Roosevelt Blvd, Key West, FL 33040
New Town
Tropical fruits, preserves, and local products.
Grocery Stores & Neighborhood Markets
Fausto’s Food Palace (Old Town)
522 Fleming St, Key West, FL 33040
Old Town – Walkable
Fausto’s Food Palace (Mid-Town)
1105 Truman Ave, Key West, FL 33040
Near Old Town / Mid-Town
Publix Super Market
3316 N Roosevelt Blvd, Key West, FL 33040
New Town
Winn-Dixie
3300 N Roosevelt Blvd, Key West, FL 33040
New Town
The Green Pineapple
1210 Truman Ave, Key West, FL 33040
Old Town – Truman Annex
Organic and specialty foods.
Shorty’s Market
1408 Kennedy Dr, Key West, FL 33040
New Town – Key Plaza
Local market with Cuban specialties.
Sugar Apple Organic Café & Market
917 Simonton St, Key West, FL 33040
Old Town – Bahama Village
Natural and organic foods.
Eaton Street Seafood Market
520 Southard St, Key West, FL 33040
Old Town – Near Duval
Fresh seafood for visitors with kitchen access.
Clothing & Shoe Stores
Tunaskin Aquatic Apparel
409 Caroline St, Key West, FL 33040
Old Town
Birkenstock of Old Town
411 Duval St, Key West, FL 33040
Old Town
Kirby’s Closet
224 Duval St, Key West, FL 33040
Old Town
Bealls
3424 N Roosevelt Blvd, Key West, FL 33040
New Town
Key West Tropical Shirt Company
415 Duval St, Key West, FL 33040
Old Town
Locally owned since 1975.
Key West Aloe
532 Duval St, Key West, FL 33040
Old Town
Skincare, sun care, and apparel.
Island Style Clothing
715 Duval St, Key West, FL 33040
Old Town
Resort and swimwear.
Off the Wall Clothing
801 Duval St, Key West, FL 33040
Old Town
Casual apparel and souvenirs.
Jewelry Stores (Old Town)
Mel Fisher’s Treasures
1322 Duval St, Key West, FL 33040
Local Color
280 Margaret St, Key West, FL 33040
Blue Marlin Jewelry
718 Duval St, Key West, FL 33040
Gold Conch Jewelry
601 Duval St, Key West, FL 33040
Locally crafted conch and nautical jewelry.
Tropic Treasures
914 Duval St, Key West, FL 33040
Handcrafted Keys-inspired designs.
Key West Jewelers
1210 Truman Ave, Key West, FL 33040
Fine jewelry and watch repair.
Hardware & Marine Supplies
Strunk Ace Hardware
1015 Truman Ave, Key West, FL 33040
Near Old Town
Key West Marine Hardware
818 Caroline St, Key West, FL 33040
Historic Seaport
The Home Depot
2810 N Roosevelt Blvd, Key West, FL 33040
New Town
West Marine
2930 N Roosevelt Blvd, Key West, FL 33040
New Town
Murray’s Marine Supply
2200 N Roosevelt Blvd, Key West, FL 33040
New Town
Key West Bait & Tackle
2400 N Roosevelt Blvd, Key West, FL 33040
New Town
Pharmacies & Convenience Stores
CVS Pharmacy
500 Duval St, Key West, FL 33040
Old Town – Duval Street
CVS Pharmacy (Truman Ave)
530 Truman Ave, Key West, FL 33040
Old Town – Near Truman Waterfront
Walgreens
527 Duval St, Key West, FL 33040
Old Town – Lower Duval
Walgreens (New Town)
3424 N Roosevelt Blvd, Key West, FL 33040
New Town
Dennis Pharmacy Plaza
2401 N Roosevelt Blvd, Key West, FL 33040
New Town
Millie’s Sundries
305 Petronia St, Key West, FL 33040
Old Town – Bahama Village
Circle K
1100 Truman Ave, Key West, FL 33040
Near Old Town
7-Eleven
2800 N Roosevelt Blvd, Key West, FL 33040
New Town
Bicycle & Scooter Rentals (Essential Transportation)
Pirate Scooter Rentals
401 Southard St, Key West, FL 33040
Old Town – Near Duval
Island Safari Rentals
201 Duval St, Key West, FL 33040
Old Town – Cruise Terminal Area
Eaton Bikes Key West
830 Eaton St, Key West, FL 33040
Old Town – Truman Annex
Sunshine Scooters
500 Truman Ave, Key West, FL 33040
Old Town
Fun Rentals Key West
1000 Truman Ave, Key West, FL 33040
Old Town
A&M Rentals
523 Truman Ave, Key West, FL 33040
Old Town
HydroThunder of Key West
6810 Front St, Key West, FL 33040
New Town – Garrison Bight
Beach & Water Sports Gear
Key West Pro Guides
2400 N Roosevelt Blvd, Key West, FL 33040
New Town
Dive Key West Inc.
3128 N Roosevelt Blvd, Key West, FL 33040
New Town
Lazy Dog Adventures
5114 Overseas Hwy, Key West, FL 33040
Stock Island
Key West Surf Shop
930 Eaton St, Key West, FL 33040
Old Town
Shipping & Postal Services
UPS Store
2851 N Roosevelt Blvd, Key West, FL 33040
New Town – Key Plaza
FedEx Office
2610 N Roosevelt Blvd, Key West, FL 33040
New Town
Key West Main Post Office
1600 Airport Rd, Key West, FL 33040
New Town
Postal Center Plus
926 Truman Ave, Key West, FL 33040
Old Town
Medical Services & Urgent Care
Lower Keys Medical Center
5900 College Rd, Key West, FL 33040
Stock Island
Keys Urgent Care
3300 N Roosevelt Blvd, Key West, FL 33040
New Town
Key West Medical Center
1220 Simonton St, Key West, FL 33040
Old Town
Fitness & Wellness
Key West Yoga Sanctuary
1207 White St, Key West, FL 33040
Old Town – Truman Annex
Island Gym
1111 12th St, Key West, FL 33040
New Town
Key West Athletic Club
1400 Duncan St, Key West, FL 33040
Old Town
Specialty Food & Beverage (Retail)
Key West Winery
1030 Eaton St, Key West, FL 33040
Old Town
The Rum Barrel
224 Duval St, Key West, FL 33040
Old Town
Publix Liquors
3316 N Roosevelt Blvd, Key West, FL 33040
New Town
Key West Coffee Co.
513 Greene St, Key West, FL 33040
Old Town
Why This Directory Matters
This expanded directory is designed for real-world Key West needs—the moments when you need something quickly and don’t want to interrupt your vacation searching online. With clear addresses, walkability context, and neighborhood relevance, this guide helps visitors move confidently around the island.
We hope this comprehensive directory makes your Key West vacation more convenient and enjoyable. Safe travels and enjoy your stay in paradise!