The Saint Hotel Key West - Luxury Adult-Only Boutique Stay

This adults-only boutique hotel places guests in the heart of Old Town Key West, just steps from Duval Street and close to Mallory Square, the Hemingway Home, Truman Little White House, restaurants, galleries, boutiques, and waterfront attractions. Part of Marriott’s Autograph Collection, the property blends the historic Edgar House and former Memorial Hospital with an intimate 36-room hotel experience designed for adults seeking a polished Key West stay.

Rooms and suites mix classic architecture with contemporary boutique design, offering a range of layouts from cozy European-style rooms to more spacious guest rooms and loft-style accommodations. Guests can expect complimentary Wi-Fi for Marriott Bonvoy members, digital television, daily housekeeping, turndown service, room service, wake-up calls, dry-cleaning options, and attentive front-desk service.

The property’s compact Old Town setting is one of its strongest visitor advantages. A walkable location near Duval Street makes it easy to move between live music, dining, historic landmarks, shopping, sunset attractions, and late-night entertainment without relying heavily on a car. On-site conveniences include an outdoor pool with towel service, complimentary coffee and tea in the lobby, bicycle rental, concierge assistance, business center access, and valet parking.

Dining and nightlife add extra value for guests who want a complete boutique-hotel experience. Tempt Restaurant serves from morning through evening, Burgundy Bar offers the property’s signature cocktail atmosphere and happy hour, and Halo Rooftop Lounge brings open-air drinks, people-watching, and live music at 8:00 pm. Together, these spaces make the hotel more than a place to sleep—they create a stylish Old Town base for adults who want food, cocktails, music, and Key West energy close at hand.

For current room options, rates, and direct reservations, use the Reserve a Room button above.